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samedi 25 novembre 2023

The Most Important Antioxidant is Melatonin

The Power of Melatonin: Unveiling its Role Beyond Sleep

Unlocking the secrets of melatonin reveals a profound impact on health beyond its well-known role inregulating sleep. In this exploration, we delve into the depths of this powerhouse antioxidant, understanding its significance in combating diseases, particularly those rooted in mitochondrial dysfunction.

The Root Causes of Health Challenges

1. Heart Disease: A Leading Culprit

The leading cause of death globally is heart disease, fueled by oxidative stress and free radical damage. Whether induced by dietary choices, smoking, or oxidative stress, the core of the issue lies in mitochondrial dysfunction.

2. Cancer: A Cellular Perspective

Cancer, too, originates in the mitochondria. The domino effect begins with mitochondrial damage, leading to the transformation of a cell into a cancerous entity. The common denominator in these health challenges is an excess of oxidative stress.

3. Metabolic Illness: Unveiling the Connection

Metabolic illnesses, diverse in manifestation, share a common thread – mitochondrial diseases. The dysfunction that ravages the mitochondria sets the stage for ailments such as diabetes and Alzheimer's.

The Guardian of Mitochondrial Health: Melatonin

1. Beyond the Sleep Hormone

While commonly associated with sleep regulation, melatonin emerges as a powerful antioxidant. Surpassing even the renowned glutathione, melatonin not only acts as an antioxidant but also triggers other antioxidant networks.

2. Melatonin vs. Vitamin E

Comparing melatonin to vitamin E, a stalwart in heart disease prevention, underscores the former's potency. Melatonin stands out as a double-edged sword, aiding in sleep regulation and fortifying the body against oxidative stress.

3. Two Forms of Melatonin

Melatonin manifests in two forms – circulatory and subcellular. The majority resides in the mitochondria, forming a robust defense against oxidation and free radical damage. The pineal gland's melatonin serves as a backup, emphasizing the critical role of the subcellular variant.

Unraveling the Intricacies of Melatonin

1. Sleep and Beyond: The Pineal-Powered Melatonin

Traditionally viewed as the hormone of darkness, melatonin's role extends beyond sleep. The pineal gland's melatonin is stimulated by darkness, vital for quality sleep and overall health.

2. Sunlight: A Surprising Catalyst

New revelations highlight sunlight, particularly near infrared wavelengths, as a potent stimulator of intracellular melatonin. Beyond vitamin D, sunlight becomes a crucial factor in maintaining optimal melatonin levels.

3. Modern Challenges: Artificial Light

The shift from natural to artificial light sources, including LEDs and blue light from electronic devices, poses a threat to melatonin levels. Studies link artificial light exposure to cognitive challenges, emphasizing the importance of natural light.

Real-world Examples: Nature's Antioxidant Buffet

Drawing inspiration from individuals living amidst adverse dietary habits but thriving in health, we find that continuous exposure to natural elements compensates for dietary shortcomings. The anecdotal evidence showcases the resilience bestowed by an abundance of antioxidants.

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